Ignacio Lizasoain Selected Research

Stroke (Strokes)

2/2022	Cav-1 Protein Levels in Serum and Infarcted Brain Correlate with Hemorrhagic Volume in a Mouse Model of Thromboembolic Stroke, Independently of rt-PA Administration.
1/2022	Neutrophil Extracellular Trap Targeting Protects Against Ischemic Damage After Fibrin-Rich Thrombotic Stroke Despite Non-Reperfusion.
1/2021	Circadian Biology and Stroke.
1/2021	New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases.
1/2021	Role of TLR4 in Neutrophil Dynamics and Functions: Contribution to Stroke Pathophysiology.
11/2019	Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance.
10/2019	Role of TLR4 (Toll-Like Receptor 4) in N1/N2 Neutrophil Programming After Stroke.
1/2019	Toll-like receptor 4 regulates subventricular zone proliferation and neuroblast migration after experimental stroke.
1/2019	Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice.
1/2018	TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models.

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Ignacio Lizasoain Research Topics

Disease

50	Stroke (Strokes) 02/2022 - 01/2002
20	Brain Ischemia (Cerebral Ischemia) 10/2021 - 01/2003
20	Infarction (Infarctions) 01/2017 - 11/2002
18	Ischemia 10/2019 - 01/2003
17	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 02/2022 - 11/2002
15	Ischemic Stroke 06/2022 - 06/2005
14	Inflammation (Inflammations) 11/2019 - 10/2004
4	Brain Injuries (Brain Injury) 01/2015 - 03/2003
3	Iron Overload 01/2018 - 12/2012
3	Atherosclerosis 03/2017 - 09/2007
3	Hypoxia (Hypoxemia) 08/2015 - 12/2010
3	Neuroinflammatory Diseases 07/2013 - 04/2005
3	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 12/2010 - 06/2005
3	Necrosis 07/2005 - 03/2003
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 04/2022 - 01/2018
2	Thrombosis (Thrombus) 01/2022 - 11/2019
2	Thrombotic Stroke 01/2022 - 11/2019
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2021 - 09/2007
2	Hemorrhage 01/2018 - 01/2017
2	Brain Infarction 01/2018 - 01/2012
2	Encephalitis (Encephalitis, Rasmussen) 12/2013 - 09/2008
2	Multiple Sclerosis 10/2011 - 06/2006
2	Hypertension (High Blood Pressure) 01/2006 - 06/2005
2	Seizures (Absence Seizure) 12/2005 - 09/2003
2	Cerebral Infarction 12/2003 - 03/2003
1	Myocardial Infarction 06/2022
1	Craniocerebral Trauma (Head Injury) 10/2021

Drug/Important Bio-Agent (IBA)

11	Toll-Like Receptor 4IBA 06/2022 - 03/2007
9	Neuroprotective AgentsIBA 01/2022 - 03/2003
9	Glutamic Acid (Glutamate)FDA Link 10/2021 - 03/2003
8	Oxygen (Dioxygen)IBA 02/2022 - 03/2005
7	Tissue Plasminogen Activator (Alteplase)FDA Link 02/2022 - 01/2011
7	Proteins (Proteins, Gene)FDA Link 02/2022 - 01/2006
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2015 - 11/2002
6	Glucose (Dextrose)FDA LinkGeneric 02/2022 - 03/2005
5	CytokinesIBA 03/2017 - 08/2004
5	Rosiglitazone (Avandia)FDA Link 04/2014 - 02/2006
5	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 04/2009 - 09/2004
5	PPAR gammaIBA 03/2009 - 04/2005
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2005 - 08/2003
4	LigandsIBA 11/2019 - 05/2007
4	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2018 - 01/2003
4	CannabinoidsIBA 01/2017 - 12/2010
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 04/2009 - 07/2005
4	Adenosine Triphosphate (ATP)IBA 11/2005 - 11/2003
3	IronIBA 01/2018 - 12/2012
3	Thrombin FDA Link 01/2017 - 01/2011
3	Indicators and Reagents (Reagents)IBA 01/2016 - 10/2004
3	EnzymesIBA 01/2016 - 01/2003
3	NitrogenIBA 01/2015 - 11/2005
3	Cytidine Diphosphate Choline (Citicoline)IBA 09/2013 - 03/2005
3	Protein Isoforms (Isoforms)IBA 03/2012 - 09/2003
3	ADAM17 ProteinIBA 06/2006 - 03/2003
3	ProstaglandinsIBA 02/2006 - 06/2005
2	Pharmaceutical PreparationsIBA 02/2022 - 03/2017
2	FibrinIBA 01/2022 - 11/2019
2	Deoxyribonuclease I (Nickase)IBA 01/2022 - 11/2019
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2018
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 11/2019 - 12/2014
2	NestinIBA 01/2019 - 05/2015
2	Immunoglobulin G (IgG)IBA 01/2018 - 01/2017
2	Messenger RNA (mRNA)IBA 01/2018 - 03/2012
2	EndocannabinoidsIBA 01/2017 - 07/2013
2	1,1-dimethylbutyl-1-deoxy-Delta(9)-THCIBA 01/2017 - 01/2012
2	LipidsIBA 01/2016 - 09/2008
2	KynurenineIBA 01/2016 - 12/2014
2	Bromodeoxyuridine (BrdU)IBA 05/2015 - 11/2014
2	InterleukinsIBA 01/2015 - 12/2003
2	InterferonsIBA 01/2015 - 10/2011
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2015 - 04/2009
2	Metalloproteases (Metalloproteinases)IBA 01/2015 - 03/2003
2	lipoxin A4IBA 04/2014 - 03/2009
2	Sirtuin 1IBA 09/2013 - 08/2013
2	sirtinolIBA 09/2013 - 08/2013
2	Cannabinoid Receptor AgonistsIBA 12/2010 - 09/2007
2	Immunoglobulin A (IgA)IBA 04/2009 - 05/2007
2	Peroxidase (Myeloperoxidase)IBA 04/2009 - 10/2004
2	2,4-thiazolidinedione (thiazolidinedione)IBA 02/2006 - 09/2005
2	cyclopentenoneIBA 02/2006 - 09/2005
2	Interleukin-6 (Interleukin 6)IBA 01/2006 - 12/2003
2	AntioxidantsIBA 11/2005 - 11/2003
2	Nitric Oxide Synthase (NO Synthase)IBA 03/2005 - 08/2003
2	salicylhydroxamic acid (SHAM)IBA 08/2003 - 11/2002
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 03/2003 - 01/2002
1	Insulin ReceptorIBA 04/2022
1	ProinsulinIBA 04/2022
1	N- alpha- benzoyl- N5- (2- chloro- 1- iminoethyl)- L- ornithine amideIBA 11/2019
1	Transcription Factors (Transcription Factor)IBA 11/2019
1	XenobioticsIBA 11/2019
1	Complementary DNA (cDNA)IBA 10/2019
1	Memantine (Namenda)FDA Link 01/2019
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019
1	HMGB1 Protein (HMG1)IBA 01/2019
1	Temozolomide (Temodar)FDA LinkGeneric 01/2019

Therapy/Procedure

11	Therapeutics 01/2021 - 09/2005
4	Ligation 01/2022 - 12/2012
2	Thrombolytic Therapy 02/2022 - 01/2022
1	Renal Dialysis (Hemodialysis) 10/2021
1	Thrombectomy 01/2021
1	Investigational Therapies (Experimental Therapy) 01/2019